P04-03 Does physical activity improve an interaction between motor control and cognitive functions in elderly?

Abstract Background Normal aging is associated with progressive functional loss in many cognitive domains, including working memory, attention (van Raalten et al., 2008) and executive functions (Nyberg et al., 2008), responsible for the control of behavioral activities (Miller & Cohen, 2001). Research aim was to evaluate postural control and executive function during dual tasking in physically active and inactive old adults. Methods Participants were 42 older healthy human males and females (Mean age: 70.17±6.08 years). Posturography method with a single piezoelectric force plate was used to measure postural sway activity. For the evaluation of cognitive functions, we used Word Memory task with ten audio-recorded words (Lithuanian nouns) in each trial, and the Mathematical Processing Task, where negative or positive one-digit integer-numbers (10 in total) were presented in each trial at 2-second intervals. Physical activity of participants was evaluated according to WHO recommendations. Results The study showed that there was a strong correlation between physically active time spent and balance behavior. The balance of physically active older people was statistically significantly more stable when they performed cognitive tasks than that of those who were physically inactive. Dual-task interferences on postural sway were evident in both Word Memory task and the Mathematical Processing Task conditions. Dual-task effect on Mathematical Processing Task and Word Memory task was not statistically different. Discussion Taken together, we suggest that physical activity improves proprioceptive control which also improves balance control. In dual tasking, more attention is required in cognitive tasking, so better proprioception allows for better balance control with fewer attention resources. However, it is also evident that participants can reduce sway activity and increase balance stability by increasing attentional control.


Background
Normal aging is associated with progressive functional loss in many cognitive domains, including working memory, attention (van Raalten et al., 2008) and executive functions (Nyberg et al., 2008), responsible for the control of behavioral activities (Miller & Cohen, 2001). Research aim was to evaluate postural control and executive function during dual tasking in physically active and inactive old adults. Methods Participants were 42 older healthy human males and females (Mean age: 70.17AE6.08 years). Posturography method with a single piezoelectric force plate was used to measure postural sway activity. For the evaluation of cognitive functions, we used Word Memory task with ten audio-recorded words (Lithuanian nouns) in each trial, and the Mathematical Processing Task, where negative or positive one-digit integer-numbers (10 in total) were presented in each trial at 2-second intervals. Physical activity of participants was evaluated according to WHO recommendations.

Results
The study showed that there was a strong correlation between physically active time spent and balance behavior. The balance of physically active older people was statistically significantly more stable when they performed cognitive tasks than that of those who were physically inactive. Dual-task interferences on postural sway were evident in both Word Memory task and the Mathematical Processing Task conditions. Dual-task effect on Mathematical Processing Task and Word Memory task was not statistically different.

Discussion
Taken together, we suggest that physical activity improves proprioceptive control which also improves balance control. In dual tasking, more attention is required in cognitive tasking, so better proprioception allows for better balance control with fewer attention resources. However, it is also evident that participants can reduce sway activity and increase balance stability by increasing attentional control. Keywords: Dual tasking Abstract citation ID: ckac095.058 P04-04 Non-invasive biomarkers with high discriminant ability indicative of musculoskeletal health with ageing

Background
The use of large-scale pooled analyses and data sharing is a potential source to generate evidence to address complex scientific challenges and develop strategies to promote healthy ageing. However, the success of such analyses depends on robust measurements of musculoskeletal (MSK) health in ageing. Simple tests indicative of MSK health and suitable for use with older people are required. This study aims to assess the discriminatory ability of a combination of routine physical function tests and novel measures, notably muscle mechanical properties and ultrasound imaging of thigh composition (relative contribution of muscle and subcutaneous adipose tissue) to classify healthy individuals according to their age and gender.

Methods
This cross-sectional study included 138 community-dwelling, self-reported healthy males and females (65 young, mean ageAESD = 25.7AE4.8 years; 73 older, 74.9AE5.9 years). Handgrip strength; quadriceps strength; respiratory peak flow; timed up and go; stair climbing; anterior thigh tissue thickness (using ultrasound imaging), muscle mechanical properties (stiffness, tone and elasticity; Myoton technology); and self-reported health related quality of life (SF36) were assessed. Stepwise linear discriminant analysis was used to classify cases based on criterion variable derived from the known effects of age on physical function.

Results
Combining conventional physical function tests with novel measures, revealed two discriminant functions which significantly (Wilks's = 0.05, 0.34; p>0.001) classified 89% of grouped cases with 11% error rate using leave-one-out crossvalidation. Seven variables associated with grip strength, peak flow, timed up and go, anterior thigh thickness, and muscle mechanical properties demonstrated high discriminant ability (p>0.05 correlation with discriminant functions) to classify healthy people.